Clec4b2, also known as mDCAR1, is a member of the DCIR/DCAR family. Expression of Clec4b2 was strongly tissue dependent. Clec4b2 expression on DCs was restricted to the CD8(+) DC subset in spleen and thymus and on subpopulations of CD11b(+) myeloid cells in bone marrow and spleen, whereas the molecule was not detectable on both cell types in lymph nodes and peripheral blood. Clec4b2 is a functional receptor on cells of the immune system and provides further insights into the regulation of immune responses by CLRs.
References
Katayama S. et al., 2005, Science. 309 (5740): 1564-6.
Kaden SA. et al., 2009, J Immunol. 183 (8): 5069-78.
Skarnes WC. et al., 2011, Nature. 474 (7351): 337-42.
Rat CLEC4B2 / mDCAR1 Gene ORF cDNA clone expression plasmid,without any tag, Related Products
