CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer.
References
Hart AB. et al., 2012, PLoS One. 7 (8): e42646.
Xu J. et al., 2012, BMC Cancer. 12: 243.
Jo J. et al., 2012, Obesity (Silver Spring). 20 (8): 1683-7.
Rat CDH13 / Cadherin-13 / H Cadherin Gene ORF cDNA clone expression plasmid,without any tag, Related Products
